Saskatoon, Saskatchewan

Prairie Harm Reduction, which operated Saskatoon's only supervised drug consumption site and provided support services to people living with addictions, closed entirely earlier in April 2026, resulting in more than 100 workers being laid off. The closure has led to increased pressure on emergency services and hospitals dealing with overdose-related calls.

Vendasta has confirmed layoffs at its Saskatoon office, cutting 20 employees, roughly 3% of its workforce. Most affected roles were in content creation. The company attributed the reductions to shifts in the software market driven by artificial intelligence.

Saskatchewan Polytechnic is cutting 14 jobs through layoff notices to out-of-scope employees and leaving 8 vacant positions unfilled due to a significant decline in international student enrolment caused by federal immigration policy changes. This is the second round of layoffs in 2025, following 27 job cuts in April, as the institution faces a budget shortfall of up to $15 million for the 2025-26 academic year.